Bronchodilator responsiveness in patients with COPD
نویسندگان
چکیده
منابع مشابه
Bronchodilator responsiveness in patients with COPD.
The degree of acute improvement in spirometric indices after bronchodilator inhalation varies among chronic obstructive pulmonary disease (COPD) patients, and depends upon the type and dose of bronchodilator and the timing of administration. Acute bronchodilator responsiveness at baseline was examined in a large cohort of patients with moderate-to-very-severe COPD participating in the Understan...
متن کاملAirway wall thickness is increased in COPD patients with bronchodilator responsiveness
RATIONALE Bronchodilator responsiveness (BDR) is a common but variable phenomenon in COPD. The CT characteristics of airway dimensions that differentiate COPD subjects with BDR from those without BDR have not been well described. We aimed to assess airway dimensions in COPD subjects with and without BDR. METHODS We analyzed subjects with GOLD 1-4 disease in the COPDGene® study who had CT airw...
متن کاملImpact of bronchodilator responsiveness on quality of life and exercise capacity in patients with COPD.
BACKGROUND Bronchial variability in COPD patients may be a phenotypic feature associated with clinical characteristics and differential treatment response. We analyzed whether symptoms, quality of life, and exercise capacity varied in COPD patients as a function of bronchodilator test results, and compared responses to an exercise program. METHODS A positive bronchodilator test result was def...
متن کاملEarly COPD patients with lung hyperinflation associated with poorer lung function but better bronchodilator responsiveness
BACKGROUND It is unknown whether aggressive medication strategies should be used for early COPD with or without lung hyperinflation. We aimed to explore the characteristics and bronchodilator responsiveness of early COPD patients (stages I and II) with/without lung hyperinflation. METHODS Four hundred and six patients with COPD who performed both lung volume and bronchodilation tests were ret...
متن کاملAcute bronchodilator responsiveness and health outcomes in COPD patients in the UPLIFT trial
BACKGROUND Debate continues as to whether acute bronchodilator responsiveness (BDR) predicts long-term outcomes in COPD. Furthermore, there is no consensus on a threshold for BDR. METHODS At baseline and during the 4-year Understanding Potential Long-term Improvements in Function with Tiotropium (UPLIFT®) trial, patients had spirometry performed before and after administration of ipratropium ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: European Respiratory Journal
سال: 2008
ISSN: 0903-1936,1399-3003
DOI: 10.1183/09031936.00129607